By Josh Bloom — August 21, 2019 Suffice it to say that most people are genuinely clueless when it comes to chemistry, let alone, evaluation of the risks and/or benefits of different chemicals. How else could you possibly explain the following disconnect -supplement companies are marketing their dubious products to children and it’s working. One-third of the kids in the US is taking a supplement or vitamin.
There is one obvious explanation; “chemical terror groups,” like EWG and NRDC (1), and internet screwballs like Mike Adams and Joe Mercola, have a similar business model: fear of chemicals, the more irrational the better, means more donations or sales.
THREE CHEERS FOR THE DIETARY SUPPLEMENTS INDUSTRY
Many of the same people who want to shove their kids into a lead-lined safe room in the basement when someone walks by with a can of Raid or diet soda are unknowingly feeding them multiple unknown chemicals by giving them dietary supplements, virtually none of which are useful and some are dangerous.
I have to tip my hat to the supplement industry. Just like the organic food industry, it has managed to pull the sustainable wool over the eyes of a whole bunch of Americans by convincing them that what they sell is chemical-free and harmless. It is anything but – something Dr. Henry Miller and I wrote about recently for Issues and Insights (See Will Dangerous Dietary Supplements Finally Be Reined In?)
It is painfully ironic that parents – perhaps the group that is most terrified about everyday chemicals – are unwittingly feeding them to their kids based on the false hope that they will prevent diseases (like the common cold) or treat conditions (like ADHD and autism).
KIDS ARE FAIR GAME
A recent article in the Washington Post revealed that about 5% of dietary supplement marketing targets children. A “hot” product now is elderberry gummies, which are supposed to prevent colds (2). In a recent study published in JAMA Pediatrics, researchers at the Chan School of Public Health at Harvard concluded that one-third of US children take dietary supplements, mostly vitamins, melatonin, and fatty acids.
“Many of the most commonly used supplements, including multivitamins, are implicated in preventable adverse drug events among this population.
D. Qato, et. al., JAMA Pediatr. 2018;172(8):780-782. doi:10.1001/jamapediatrics.2018.1008
Not all supplements are equal or equally harmful. An article in the June issue of The Journal of Adolescent Health documented 977 supplement–related adverse event reports (single supplements only) in people younger than age 25 between 2004-2015. Although adverse events were much more common in dietary and herbal supplements that were supposed to “treat” a condition (3), there were still problems with vitamins,
“Consumption of dietary supplements sold for weight loss, muscle building, and energy involved increased risks for severe medical events compared with vitamins. Proactive enforcement of regulations is needed to reduce access and consumption among children, adolescents, and young adults.”
S.B. Austin, et. al., June 18, 2018. doi:10.1001/jamapediatrics.2018.1008
THE PROBLEM ISN’T JUST THE SUPPLEMENT. WHAT’S IN THE BOTTLE?
Perhaps more disturbing is a 2019 article in Hepatology Communications, in which researchers were trying to determine which supplements cause liver damage. The study does not get that far, but it is useful nonetheless, The group first determined whether the label accurately represents what is in the bottle. It’s a coin flip. Victor J. Navarro, M.D. of the Department of Digestive Disease and Transplantation at Albert Einstein Medical Center in Philadelphia and colleagues from five other major medical centers in the US examined 272 herbal and dietary supplements and found that 51% (!) of the labels were inaccurate.
In particular:
- “Of the 272 products tested, only 132 had labels that accurately reflected the compounds identified by chemical analysis”
- “140 (51%) were mislabeled. These 140 products lacked at least one of the listed compounds (number of ingredients ranged from 1 to 21)”
- “55 products contained compounds not listed on the label, including 2 that were pharmaceuticals.
- The overall mislabeling rate was 51%, and rates were higher for steroidal (82%) than botanical (44%) and vitamin (49%) products.
In other words, there is no way to know what parents are giving their kids because half the time the label is inaccurate. So even if a given supplement “works” for something or other it may or may not be in the bottle and if it is, it can be contaminated.
WHY SHOULD KIDS TAKE SUPPLEMENTS AT ALL?
That’s an easy one, thanks to ACSH advisor Dr. David Seres, director of medical nutrition, Columbia University Irving Medical Center, New York Presbyterian Hospital. They shouldn’t.
“It is perpetually frustrating to me that parents are willing to feed untested and unproven nostra and potions to their children, exposing them to potential harm with little likelihood of benefit, simply because they are touted as “natural” or “nutritional”, while at the same time dismissing scientific fact simply because it is scientific.”
David Seres, M.D., private communication, 8/20/19
It is mind-boggling that so many people are terrified of chemicals that they avoid touching cash register receipts, or won’t eat anything not labeled GM-free, blithely feed their kids who-knows-what because they perceive supplements as safe, natural, and chemical-free.
There ought to be a law (4).
NOTES:
(1) EWG is short for the Environmental Working Group. NRDC stands for the Natural Resources Defense Council. It is difficult to determine which group is worse scientifically at any given time. Perhaps they take turns. Both groups are run by highly-paid lawyers and poly-majors, not scientists. If you want to “favor” NRDC then read NRDC’s Hitler-Pesticide Video Worthy Of Joseph Goebbels.
(2) There is no evidence that elderberry prevents colds but it may help people feel better sooner.
(3) Anything that treats or prevents a condition or disease is a drug. This is part of the FDA’s definition of what a drug is.
(4) There is, more or less. In 2015 New York Attorney General Eric T. Schneiderman sent cease-and-desist letters to GNC, Target, Walgreens, and Walmart after a study commissioned by his office found that supplement labels sold in the state were woefully lacking. The following month he issued a statement announcing an agreement that his office reached with the companies in question. Both Dr. Seres and I were quoted in Schneiderman’s press release.
By Josh Bloom
Dr. Josh Bloom, the Director of Chemical and Pharmaceutical Science, comes from the world of drug discovery, where he did research for more than 20 years. The field of drug discovery involves chemistry, biochemistry, toxicology, and pharmacology – skills that he has used to write on a wide variety of topics since he joined ACSH in 2010. One of the topics he has tackled is the so-called “opioid crisis.” He is now recognized as an expert in this area and was the first journalist to write a nationally published opinion piece about the unintended consequences of a governmental crackdown on prescription pain medications (New York Post, 2013). Since that time he has published more than 20 op-eds in regional and national newspapers on different aspects of the crisis. In that same year, he testified at an FDA hearing, where he noted that fentanyl was the real danger, something that would be proven years later. At that time almost no one had heard of the drug.
He was also the first writer (2016) to study, dissect and ultimately debunk the manipulated statistics used by the CDC to justify its recommendations for opioid prescribing, which have resulted in Draconian requirements for prescribing pain medications as well as government-mandated, involuntary tapering of patients receiving opioid treatment, both of which have caused great harm and needless suffering to chronic pain patients. His 2016 article, “Six Charts Designed to Confuse You,” is the seminal work on CDC deception and has been adopted by patient advocacy groups and individuals and has been sent to governors and state legislatures.
Dr. Bloom earned his Ph.D. in organic chemistry from the University of Virginia, followed by postdoctoral training at the University of Pennsylvania. His career in drug discovery research began at Lederle Laboratories, which was acquired by Wyeth in 1994, which itself was acquired by Pfizer in 2009. During this time he participated in research in a number of therapeutic areas, including diabetes and obesity, antibiotics, HIV/AIDS, hepatitis C, and oncology. His group discovered the novel antibiotic Tygacil®, which was approved by the FDA for use against resistant bacterial infections in 2005. He is the author of 25 patents, and 35 academic papers, including a chapter on new therapies for hepatitis C in Burger’s Medicinal Chemistry, Drug Discovery and Development, 7th Edition (Wiley, 2010), and has given numerous invited lectures about how the pharmaceutical industry really works.
Dr. Bloom joined the American Council on Science and Health in 2010 as ACSH’s Director of Chemical and Pharmaceutical Sciences, and has since published more than 60 op-eds in numerous periodicals, including The Wall Street Journal, Forbes, New Scientist, The New York Post, National Review Online, The Boston Herald, and The Chicago Tribune, and given numerous radio and television interview on topics related to drugs and chemicals. In 2014, Dr. Bloom was invited to become a featured writer for the site Science 2.0, where he wrote more 75 pieces on a broad range of topics.